Increased intracranial pressure as a result of clear cause.  Some causes might include:  stroke (subarachnoid hemorrhage), Cerebral blood clots (dural venous thrombosis), Kidney failure, liver failure, sleep apnea, Meningitis (bacterial or viral), Lyme disease, Human immunodeficiency virus (HIV), Poliomyelitis, Coxsackie B viral encephalitis, Guillain-Barre syndrome, Infectious mononucleosis, Syphilis, and Malaria.

Certain drugs have also been associated with increased intracranial pressure such as:  Tetracycline, Minocycline, Isotretinoin (Accutane),  All-trans retinoic acid (used in the treatment of promyelocytic leukemia),Excessive ingestion of Vitamin A (hypervitaminosis A), Amiodarone, Nitofurantoin, Lithium, Levonorgestral (Norplant), Growth hormone treatments, Steroid withdrawal.