For more on these pathological cofactors and how they relate to Chiari and EDS (a genetic condition): https://chiaribridges.org/overview-chiari-comorbidities-etiological-pathological-cofactors/

For more information, see:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887504/

http://onlinelibrary.wiley.com/doi/10.1002/ajmg.c.31549/full

*Both of these studies are published in the US National Library of Medicine National Institutes of Health, so our Neurosurgeons have no excuse for not knowing about them.